Understanding Lab Tests for Thyroid Eye Disease
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Thyroid Eye Disease (TED), also known as Graves' Ophthalmopathy, is an autoimmune condition that affects the tissues around the eyes, causing inflammation, swelling, and potentially vision problems. While the diagnosis is primarily made through clinical examination and imaging, blood tests play a crucial role in identifying the underlying autoimmune activity that drives this condition.
Recommended Test
Thyroid-Stimulating Immunoglobulin (TSI)
This test measures TSI antibodies in the blood, which are strongly associated with Thyroid Eye Disease. Elevated TSI levels indicate active autoimmune activity that can infiltrate the tissues around the eyes, causing the characteristic inflammation and swelling seen in this condition. This test is essential for confirming the autoimmune basis of the eye symptoms.
2907 reviews
The Role of Blood Testing in Thyroid Eye Disease
Thyroid Eye Disease is closely associated with autoimmune thyroid conditions, particularly Graves' disease. Specific antibodies in the blood can trigger inflammation in the eye tissues. Blood testing helps identify these antibodies, confirm the autoimmune nature of the condition, and guide treatment decisions.
Understanding Your Results
Elevated TSI levels suggest active autoimmune thyroid disease that may be affecting the eye tissues. However, it's important to note that not all patients with high TSI develop eye symptoms, and some patients with eye disease may have normal or only slightly elevated levels. Your healthcare provider will interpret these results alongside your symptoms and clinical examination.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
