Understanding Lab Tests for Thiamine Overdose
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Thiamine overdose, while rare, can occur when excessive amounts of vitamin B1 are consumed, typically through high-dose supplements. Symptoms may include restlessness, fluid retention, nausea, weakness, rapid pulse, irregular heartbeat, low blood pressure, and hives. A specific blood test can confirm elevated thiamine levels in the body.
Recommended Test
Vitamin B1 (Thiamine) LC/MS/MS
This highly accurate test uses liquid chromatography-tandem mass spectrometry (LC/MS/MS) to precisely measure thiamine levels in the blood. It can detect elevated concentrations that may be causing overdose symptoms such as restlessness, fluid retention, nausea, weakness, rapid pulse, irregular heartbeat, low blood pressure, and hives.
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Confirming Thiamine Overdose Through Testing
Because the symptoms of thiamine overdose can overlap with other conditions, laboratory testing is essential to confirm whether elevated vitamin B1 levels are the cause. This allows healthcare providers to make informed decisions about treatment and supplement adjustments.
Understanding Your Results
Elevated thiamine levels on this test, when combined with compatible symptoms, can confirm a thiamine overdose. Your healthcare provider can then recommend appropriate steps, which may include discontinuing or reducing thiamine supplements and monitoring your recovery.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of suspected thiamine overdose.
