Understanding Lab Tests for Tertiary Hyperparathyroidism
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Tertiary hyperparathyroidism is a rare endocrine disorder that develops when chronic hyperparathyroidism causes one or more parathyroid glands to become enlarged and produce excessive amounts of parathyroid hormone (PTH). This condition typically occurs after prolonged secondary hyperparathyroidism and results in elevated calcium levels in the blood.
Recommended Test
Parathyroid Hormone (PTH), Intact
This test measures the level of intact parathyroid hormone in the blood, which is the primary diagnostic marker for tertiary hyperparathyroidism. In this rare condition, chronic hyperparathyroidism causes parathyroid glands to become enlarged and autonomously produce excessive PTH, leading to elevated hormone levels and resulting in high blood calcium levels.
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Diagnosing Tertiary Hyperparathyroidism
Blood testing is essential for diagnosing tertiary hyperparathyroidism. The diagnosis relies on laboratory evidence of elevated PTH levels along with high calcium levels, which distinguishes it from other forms of hyperparathyroidism. These blood tests provide the definitive biochemical confirmation needed for accurate diagnosis.
Understanding Your Results
In tertiary hyperparathyroidism, PTH levels are typically elevated along with high calcium levels. This combination helps healthcare providers distinguish tertiary hyperparathyroidism from primary and secondary forms of the condition. Additional tests measuring calcium, phosphorus, and vitamin D may also be ordered to provide a complete assessment of mineral metabolism.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
