Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Systemic candidiasis is a serious condition where Candida yeast enters the bloodstream and spreads throughout the body. Unlike localized Candida infections (such as thrush or vaginal yeast infections), systemic candidiasis can be life-threatening and requires prompt diagnosis and treatment.
This comprehensive antibody test measures three different types of immune responses (IgG, IgA, and IgM) to Candida albicans, the most common species causing systemic infections. Elevated levels of all three antibody types strongly suggest a systemic Candida infection, indicating that the yeast has entered the bloodstream and triggered a significant immune response throughout the body.
Systemic candidiasis can be challenging to diagnose because its symptoms often mimic other serious infections. Blood testing for specific Candida antibodies is essential for confirming the diagnosis, as it can detect the body's immune response to the invasive fungal infection.
The presence of multiple antibody types (IgG, IgA, and IgM) indicates different stages and locations of immune response. IgM antibodies typically appear first during an active infection, while IgG antibodies indicate a more established immune response. IgA antibodies are often associated with mucosal infections that may have progressed to systemic involvement.
Systemic candidiasis is a medical emergency that requires immediate professional treatment. This information is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.