Understanding Lab Tests for Selenium Toxicity
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Selenium toxicity, also known as selenosis, occurs when the body accumulates excessive amounts of selenium, typically from over-supplementation or consuming foods grown in selenium-rich soil. While selenium is an essential trace mineral, too much can lead to serious health complications including hair loss, neurological damage, and systemic toxicity.
Top Recommended Test
Selenium
This blood test directly measures selenium levels in the serum. Elevated selenium concentrations can confirm selenium toxicity or selenosis. This test is particularly valuable when symptoms like hair loss, nausea, irritability, fatigue, and nerve damage are present, as these are classic signs of selenium overconsumption.
2907 reviews
Diagnosing Selenium Toxicity
Since symptoms of selenium toxicity can mimic other conditions, laboratory testing is essential for confirming elevated selenium levels in the body. These tests directly measure selenium concentrations and provide objective evidence of toxicity, enabling healthcare providers to make accurate diagnoses and develop appropriate treatment plans.
Other Relevant Tests
Selenium, 24-Hour Urine
This comprehensive urine test measures selenium excretion over a 24-hour period. High levels of selenium in the urine strongly indicate selenium toxicity or selenosis. This test is especially useful for detecting excessive selenium exposure and monitoring the body's ability to eliminate excess selenium, particularly when symptoms include garlicky breath, hair loss, fatigue, irritability, and neurological damage.
2907 reviews
Understanding Test Results
Both blood and urine selenium tests provide complementary information about selenium status. Blood selenium reflects recent intake and current circulating levels, while urine selenium indicates the body's excretion of excess selenium. Together, these tests offer a comprehensive assessment of selenium toxicity and help guide treatment decisions.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. If you suspect selenium toxicity, discontinue selenium supplementation and seek medical attention promptly.
