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Seizures are episodes of abnormal electrical activity in the brain that cause temporary disturbances in movement, behavior, sensation, or consciousness. They are caused by disrupted neurotransmitter function from factors including severe vitamin B6 deficiency, which affects GABA production and brain electrical stability. The Vitamin B6 test is the most important test for identifying this treatable nutritional cause of seizures.
Seizures are caused by abnormal electrical activity in the brain that disrupts normal neurotransmitter function. Specific causes include severe vitamin B6 deficiency (especially in infants), electrolyte imbalances like low sodium or calcium, metabolic disorders, infections such as meningitis, traumatic brain injuries, and genetic conditions. In some cases, the exact trigger remains unknown, which is why blood testing helps identify treatable underlying factors like nutritional deficiencies.
The Vitamin B6 test is the most important blood test for seizures because it detects deficiencies that directly affect neurotransmitter production, particularly GABA, which regulates brain electrical activity. Severe B6 deficiency can cause seizures that do not respond to standard anti-seizure medications until the deficiency is corrected. This test is especially critical for newborns and infants experiencing unexplained seizures. Additional metabolic panels may be recommended to check electrolyte levels like sodium, calcium, and glucose that can also trigger seizure activity when imbalanced.
You should get tested if you or your child experiences unexplained seizures, especially in infancy or early childhood. Testing is crucial when seizures do not respond well to standard medications, when there is no clear cause identified through neurological examination, or if seizures are accompanied by developmental delays or feeding difficulties. Early blood testing can identify treatable nutritional deficiencies like vitamin B6 deficiency and prevent future episodes.
What this means
Your vitamin B6 levels are below the optimal range, which may explain symptoms like persistent fatigue, low energy, or mood changes. While not severely deficient, this level suggests your body may not have enough B6 to support optimal energy production, nerve function, and immune health.
Recommended actions
Increase B6-rich foods like chicken, turkey, salmon, chickpeas, and bananas in your diet
Consider a B-complex supplement after discussing with your healthcare provider
Reduce alcohol consumption as it depletes vitamin B6 stores
Retest in 6-8 weeks after making dietary changes or starting supplementation
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