Understanding Lab Tests for Secondary Hyperparathyroidism
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Secondary hyperparathyroidism is a condition where the parathyroid glands produce excessive parathyroid hormone (PTH) in response to chronically low calcium levels or other underlying conditions such as vitamin D deficiency or chronic kidney disease. Unlike primary hyperparathyroidism, this condition develops as a compensatory response to correct calcium imbalances in the body.
Recommended Test
Parathyroid Hormone (PTH), Intact
This test measures the intact parathyroid hormone in the blood and is the primary diagnostic tool for secondary hyperparathyroidism. Elevated PTH levels indicate that the parathyroid glands are overproducing hormone in response to low calcium levels, often caused by underlying conditions like vitamin D deficiency or chronic kidney disease. This test is essential for confirming the diagnosis and monitoring treatment response.
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Diagnosing Secondary Hyperparathyroidism
Blood testing is the primary method for diagnosing secondary hyperparathyroidism. The key diagnostic marker is measuring parathyroid hormone levels, which become elevated as the glands work overtime to maintain proper calcium balance. Early detection through lab testing is crucial to prevent complications such as bone disease, muscle weakness, and cardiovascular issues.
Understanding Your Results
In secondary hyperparathyroidism, PTH levels are typically elevated as the body attempts to compensate for calcium deficiency or impaired calcium metabolism. Your healthcare provider will interpret these results alongside other factors such as calcium, phosphorus, and vitamin D levels to determine the underlying cause and develop an appropriate treatment plan.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Early detection and proper management of secondary hyperparathyroidism can help prevent serious complications and improve quality of life.
