Understanding Lab Tests for Renovascular Hypertension

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Renovascular hypertension is a type of secondary high blood pressure caused by narrowing of the arteries that supply blood to the kidneys. While imaging studies are typically used to visualize the narrowed arteries, specialized blood tests play a crucial role in evaluating the hormonal changes that occur when kidney blood flow is compromised.

Recommended Test

Aldosterone/Plasma Renin Activity Ratio, LC/MS/MS

This specialized test measures both aldosterone levels and plasma renin activity, calculating their ratio. In renovascular hypertension, reduced blood flow to the kidneys stimulates renin release, leading to elevated plasma renin activity. This test helps identify the hormonal imbalances characteristic of kidney-related high blood pressure and can support the diagnosis when combined with clinical findings.

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The Role of Blood Testing in Renovascular Hypertension

When blood flow to the kidneys is reduced due to narrowed arteries, the kidneys respond by releasing hormones, particularly renin, which leads to increased aldosterone production. These hormonal changes are part of the body's attempt to regulate blood pressure and can be detected through specific blood tests, providing valuable information about the underlying cause of hypertension.

Understanding Your Results

Interpreting these hormone levels requires medical expertise, as results must be considered alongside clinical symptoms, blood pressure readings, and other diagnostic findings. Your healthcare provider will use this information as part of a comprehensive evaluation to determine the most appropriate treatment approach.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

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