Understanding Lab Tests for Relapsing Hepatitis A

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Relapsing Hepatitis A is a rare but documented phenomenon where patients experience a return of symptoms weeks to months after apparent recovery from their initial Hepatitis A infection. This condition requires specific blood testing to confirm the diagnosis and differentiate it from other liver-related issues.

Recommended Test

Hepatitis A IgM Antibody

This test detects IgM antibodies specific to Hepatitis A virus, which typically indicate acute or recent infection. In cases of relapsing Hepatitis A, these antibodies may reappear or remain elevated during the relapse phase, providing crucial evidence to confirm the diagnosis when symptoms return after apparent recovery.

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What is Relapsing Hepatitis A?

Most people with Hepatitis A recover completely within a few weeks to months. However, in approximately 10-15% of cases, patients may experience a relapse characterized by the return of symptoms such as fatigue, nausea, abdominal pain, and elevated liver enzymes. This relapse can occur even after patients have felt completely well for weeks.

Diagnosing Relapsing Hepatitis A

Because the symptoms of relapsing Hepatitis A can mimic other liver conditions or infections, specific blood testing is essential for accurate diagnosis. The key is detecting the resurgence of specific antibodies that indicate active or recent infection.

Understanding Your Results

A positive Hepatitis A IgM antibody test in someone who previously recovered from Hepatitis A and is experiencing a return of symptoms strongly suggests relapsing Hepatitis A. Healthcare providers will interpret these results alongside clinical symptoms and other liver function tests to make an accurate diagnosis and develop an appropriate treatment plan.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. If you suspect you may have relapsing Hepatitis A, seek medical attention promptly for proper evaluation and care.

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