Understanding Lab Tests for Recurrent Miscarriage

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Recurrent miscarriage, typically defined as the loss of two or more pregnancies before 20 weeks of gestation, is a complex condition diagnosed based on pregnancy history and clinical evaluation. While there is no single blood test to diagnose recurrent miscarriage itself, laboratory testing is fundamental for identifying underlying risk factors and genetic predispositions that may contribute to pregnancy loss.

Recommended Test

Factor V (Leiden) Mutation Analysis

This genetic test identifies the Factor V Leiden mutation, which significantly increases the risk of blood clot formation. Women with this mutation have an elevated risk of recurrent miscarriages because blood clots can form in the placenta, disrupting the vital exchange of nutrients and oxygen between mother and fetus. Identifying this mutation allows for appropriate anticoagulation therapy during future pregnancies.

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Why Blood Testing is Important for Recurrent Miscarriage

Various underlying conditions can increase the risk of recurrent pregnancy loss, including genetic clotting disorders, hormonal imbalances, and immune system abnormalities. Blood tests help identify these treatable risk factors, allowing healthcare providers to develop targeted treatment plans that may improve the chances of a successful pregnancy.

Understanding Your Results

If genetic testing reveals risk factors like the Factor V Leiden mutation, your healthcare provider can discuss preventive treatments such as blood thinners or other interventions that may help support a healthy pregnancy. Early identification and management of these risk factors is crucial for optimizing pregnancy outcomes.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Recurrent miscarriage evaluation typically involves comprehensive testing beyond genetic factors. Always consult with a healthcare provider or reproductive specialist for proper diagnosis and personalized treatment planning.

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