Understanding Lab Tests for Pulmonary Embolism
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
A pulmonary embolism (PE) is a serious condition where blood clots block arteries in the lungs, potentially causing life-threatening complications. While imaging studies like CT pulmonary angiography are the primary diagnostic tools, blood tests play a crucial supporting role in assessment and risk evaluation.
Recommended Test
D-Dimer
This test measures D-Dimer, a protein fragment produced when blood clots are broken down by the body. Elevated D-Dimer levels may indicate the presence of significant clot formation, such as occurs in pulmonary embolism. While not diagnostic alone, this test is commonly used alongside clinical assessment and imaging studies to help rule out or support the diagnosis of PE.
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The Role of Blood Testing in Pulmonary Embolism
Although there isn't a single blood test that definitively diagnoses pulmonary embolism, certain blood markers can provide valuable information about clot formation and breakdown in the body. These tests are fundamental for supporting clinical suspicion and helping healthcare providers determine the need for further imaging studies.
Understanding Test Results
It's important to note that D-Dimer can be elevated in many conditions beyond pulmonary embolism, including infection, inflammation, pregnancy, and recent surgery. Therefore, results must always be interpreted within the clinical context by a healthcare professional who can correlate findings with symptoms and other diagnostic tests.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Pulmonary embolism is a medical emergency requiring immediate professional evaluation. Always consult with a healthcare provider for diagnosis and treatment.
