Understanding Lab Tests for Protein C Deficiency
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Protein C deficiency is a rare inherited blood clotting disorder that increases the risk of developing abnormal blood clots (thrombosis). This genetic condition affects the body's natural anticoagulation system, making it difficult to prevent excessive clot formation. Accurate diagnosis requires specific blood testing to measure protein C function.
Recommended Test
Protein C Activity
This test directly measures the functional activity of protein C in the blood. Since protein C deficiency is characterized by low protein C activity levels, this test is the primary diagnostic tool for confirming this rare genetic disorder that predisposes individuals to thrombosis due to decreased anticoagulant function.
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Diagnosing Protein C Deficiency
Because protein C deficiency can present with symptoms similar to other clotting disorders, or may remain asymptomatic until a thrombotic event occurs, laboratory testing is essential for definitive diagnosis. The condition is characterized by reduced anticoagulant activity of protein C, which can be measured through specialized blood tests.
Understanding Your Results
Low protein C activity levels indicate a deficiency that may explain recurrent blood clots or family history of thrombotic events. Early diagnosis is crucial for implementing appropriate anticoagulation therapy and preventing potentially life-threatening complications such as deep vein thrombosis or pulmonary embolism.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
