Understanding Lab Tests for Prostate Cancer Metastasis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Prostate cancer metastasis occurs when cancer cells spread from the prostate to other parts of the body, such as bones, lymph nodes, or other organs. While imaging studies are typically used to confirm the location and extent of metastatic disease, blood testing plays a crucial role in monitoring disease progression and treatment response.
Recommended Test
Prostate-Specific Antigen (PSA), Ultrasensitive, Post Prostatectomy (MALES ONLY)
This highly sensitive test is specifically designed for men who have had their prostate surgically removed. Since the prostate normally produces PSA, any detectable or rising PSA levels after prostatectomy can be an early indicator of cancer recurrence or metastatic spread. This test can detect PSA at much lower levels than standard PSA tests, allowing for earlier detection of potential metastasis.
2907 reviews
The Role of Blood Testing in Metastatic Prostate Cancer
Blood tests cannot definitively diagnose metastasis on their own, but they are fundamental for detecting biochemical evidence of cancer progression. For patients who have undergone prostate removal surgery, specialized blood tests can detect even minimal levels of cancer activity that may indicate spread to distant sites.
Understanding Your Results
After prostate removal, PSA levels should be undetectable or extremely low. Rising PSA levels over time may suggest that cancer cells have spread to other areas of the body and are continuing to produce this protein. Your healthcare provider will interpret these results in the context of your overall health status and treatment history.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with your oncologist or healthcare provider for proper interpretation of test results and treatment planning.
