Understanding Lab Tests for Primary Hyperparathyroidism
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Primary hyperparathyroidism is a condition where one or more of the parathyroid glands produce excessive amounts of parathyroid hormone (PTH). This hormonal imbalance leads to elevated calcium levels in the blood, which can cause symptoms ranging from kidney stones and bone problems to fatigue and depression.
Top Recommended Test
Parathyroid Hormone (PTH), Intact
This test directly measures the level of parathyroid hormone in the blood. Primary hyperparathyroidism is characterized by overproduction of PTH, so elevated levels are a key diagnostic indicator. High PTH levels lead to increased calcium in the blood, which can cause symptoms ranging from kidney stones to fatigue and depression.
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Diagnosing Primary Hyperparathyroidism
Blood tests are the primary diagnostic tools for confirming primary hyperparathyroidism. Since this condition involves hormone overproduction and calcium metabolism disruption, specific lab tests can directly measure the key markers involved in this endocrine disorder.
Other Relevant Tests
Vitamin D
This test measures vitamin D levels, which can be elevated in primary hyperparathyroidism. High vitamin D levels may suggest that the parathyroid glands are producing too much parathyroid hormone, leading to disrupted calcium metabolism and high blood calcium levels.
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Understanding Your Results
In primary hyperparathyroidism, you would typically see elevated PTH levels along with high blood calcium. Vitamin D levels may also be affected as the body attempts to regulate calcium metabolism. These tests work together to provide a comprehensive picture of parathyroid gland function and calcium balance.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
