Understanding Lab Tests for Primary Amyloidosis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Primary amyloidosis is a rare disorder where abnormal proteins called amyloid fibrils accumulate in organs and tissues throughout the body. While definitive diagnosis typically requires tissue biopsy, blood tests play a crucial role in detecting the abnormal proteins that characterize this condition and monitoring disease progression.
Recommended Test
Kappa/Lambda Light Chains, Free with Ratio
This test measures free light chains, including lambda light chains, which are abnormal proteins that accumulate in primary amyloidosis. Elevated levels of these proteins in the blood can indicate the presence of this disorder and help healthcare providers assess disease activity and response to treatment.
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The Role of Blood Testing in Primary Amyloidosis
Blood tests are fundamental for identifying the abnormal proteins responsible for primary amyloidosis. These tests can detect elevated levels of specific proteins in the bloodstream, providing essential information for diagnosis, treatment planning, and ongoing monitoring of the condition.
Understanding Your Results
Abnormal ratios or elevated levels of free light chains may suggest the presence of primary amyloidosis or other related conditions. Your healthcare provider will interpret these results in conjunction with your symptoms, physical examination findings, and potentially additional testing to make an accurate diagnosis.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Primary amyloidosis requires specialized care from experienced medical professionals.
