Understanding Lab Tests for Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD)
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD) are conditions that affect women in the days or weeks before menstruation. While these conditions are primarily diagnosed through clinical evaluation of symptoms and their timing, blood tests play an important supporting role in identifying hormonal imbalances that may contribute to their development.
Recommended Test
Progesterone
This test measures progesterone levels in the blood. Low levels of progesterone during the luteal phase (second half) of the menstrual cycle can contribute to the development of PMS and PMDD symptoms. Testing progesterone levels can help identify if hormonal imbalances are playing a role in symptom severity and guide appropriate treatment strategies.
2907 reviews
How PMS and PMDD Are Diagnosed
There is no single blood test that can diagnose PMS or PMDD. These conditions are typically diagnosed based on symptom patterns, their relationship to the menstrual cycle, and their impact on daily functioning. However, laboratory testing is fundamental for evaluating hormonal balance and identifying potential underlying factors that may be contributing to symptoms.
The Role of Hormonal Testing
Hormonal imbalances, particularly involving progesterone, can play a significant role in the development of PMS and PMDD symptoms. Testing hormone levels can provide valuable insights into whether hormonal fluctuations are contributing to the severity of symptoms and help guide appropriate treatment approaches.
Understanding Your Results
Progesterone levels naturally fluctuate throughout the menstrual cycle, with the highest levels occurring after ovulation. The timing of the test is crucial for accurate interpretation. Your healthcare provider will consider your test results in conjunction with your symptom patterns and menstrual cycle timing to develop an appropriate treatment plan.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for proper diagnosis and treatment of PMS or PMDD symptoms.
