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Pregnancy complications are medical conditions that develop during pregnancy, labor, or delivery and can affect the health of both mother and baby. They are caused by abnormal changes in blood clotting factors, hormonal imbalances, placental problems, and increased coagulation activity as the body prepares for delivery. The Fibrinogen Activity test is the most important test for diagnosing clotting-related pregnancy complications because it measures the key protein that indicates increased risk of preeclampsia and thrombosis.
Pregnancy complications are caused by various factors including abnormal blood clotting mechanisms, placental problems, hormonal imbalances, and pre-existing health conditions. During pregnancy, your body naturally increases production of clotting factors like fibrinogen to prepare for delivery and prevent excessive bleeding. However, when these clotting mechanisms become overactive or imbalanced, serious complications can develop such as preeclampsia, placental abruption, deep vein thrombosis, and HELLP syndrome. Other contributing factors include gestational diabetes, high blood pressure, infections, autoimmune disorders, and problems with the placenta's attachment or function.
The Fibrinogen Activity test is the most important test for pregnancy complications because it measures the activity of fibrinogen, the key clotting protein that becomes elevated when you are at increased risk for preeclampsia and blood clots during pregnancy. This test helps identify dangerous changes in your blood's ability to clot before serious complications develop. The D-Dimer test is also essential because it detects protein fragments from clot breakdown, and significantly elevated levels can indicate active complications like preeclampsia or placental abruption. Together, these tests provide a comprehensive picture of your clotting status and help your healthcare provider monitor your pregnancy more closely if complications arise.
You should get tested if you experience severe headaches that do not go away, sudden swelling in your face or hands, vision changes like blurred vision or seeing spots, severe abdominal pain especially in the upper right side, sudden weight gain of more than 2 pounds in a week, or persistent leg pain or swelling in one leg. Testing is also important if you have a history of blood clots, previous pregnancy complications, high blood pressure, or if your healthcare provider detects protein in your urine or elevated blood pressure during prenatal visits. Early detection through blood testing can help prevent serious complications and protect both you and your baby.
What this means
Your fibrinogen level is elevated above the optimal range, which indicates increased inflammation in your body and higher cardiovascular risk. Elevated fibrinogen makes your blood more prone to clotting and is associated with increased risk of heart attack and stroke. This is a meaningful finding that warrants attention to reduce inflammation and protect your heart health.
Recommended actions
Adopt an anti-inflammatory diet rich in omega-3 fatty acids from fish, walnuts, and flaxseeds
Engage in regular aerobic exercise like brisk walking, swimming, or cycling for 30 minutes most days
If you smoke, prioritize quitting as smoking significantly elevates fibrinogen levels
Retest in 3-6 months after implementing lifestyle changes to monitor improvement
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