Understanding Lab Tests for Poisoning

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Poisoning occurs when harmful substances enter the body in amounts that cause adverse effects. While poisoning is primarily diagnosed based on clinical symptoms and history, specific laboratory tests play a crucial role in identifying the exact substance involved and guiding appropriate treatment.

Recommended Test

Dextro/Levo Methorphan, LC/MS/MS, Urine

This specialized test uses liquid chromatography-tandem mass spectrometry to detect and measure dextromethorphan and levomethorphan levels in urine. Elevated levels can indicate poisoning from cough medicines or other products containing these substances, particularly when patients present with symptoms like dizziness, confusion, or breathing difficulties. This test is essential for confirming suspected methorphan-related poisoning cases.

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The Role of Laboratory Testing in Poisoning Cases

Blood and urine tests are fundamental tools in poisoning cases. These tests can detect and measure specific toxins, drugs, or chemicals in the body, helping healthcare providers confirm suspected poisoning, identify unknown substances, and monitor the effectiveness of treatment interventions.

When Testing is Recommended

Laboratory testing for poisoning is typically recommended when there is a known or suspected exposure to toxic substances, when patients present with unexplained symptoms that could indicate poisoning, or when monitoring the progress of treatment for confirmed poisoning cases. The specific tests ordered depend on the suspected substance and clinical presentation.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Suspected poisoning cases require immediate medical attention. Always consult with a healthcare provider for proper diagnosis and treatment.

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