Sample results
Pleural effusion is the abnormal accumulation of excess fluid in the pleural space between the lungs and chest cavity. It is caused by conditions including congestive heart failure, pneumonia, cancer (particularly lung and ovarian cancer), pulmonary embolism, kidney disease, and liver cirrhosis. The CA-125 blood test is the most important test for identifying cancer-related pleural effusions, especially when malignancy is suspected.
Pleural effusion is caused by congestive heart failure, pneumonia, cancer (lung, breast, ovarian, and lymphoma), pulmonary embolism, kidney disease, and liver cirrhosis. Heart failure causes fluid to back up into the pleural space, while infections like pneumonia trigger inflammatory fluid accumulation. Cancer cells can block lymphatic drainage or directly produce fluid, and kidney or liver disease disrupts the body's fluid balance, leading to excess accumulation around the lungs.
The CA-125 blood test is the most important test for identifying cancer-related pleural effusions because it detects elevated tumor marker levels associated with ovarian cancer and other malignancies that commonly cause fluid buildup. When CA-125 levels are elevated in the presence of pleural effusion, it signals the need for further cancer investigation. While imaging like chest X-rays and CT scans directly visualize the fluid, blood tests like CA-125 help identify the underlying cause, particularly when malignancy is suspected. Additional blood work may include complete blood count, kidney and liver function tests, and other markers to evaluate heart failure, infection, or inflammatory conditions.
You should get tested if you experience shortness of breath, chest pain that worsens with deep breathing or coughing, persistent dry cough, or difficulty breathing when lying flat. Get evaluated immediately if you have fever with breathing difficulties, unexplained weight loss along with respiratory symptoms, or known cancer with new breathing problems. Early testing helps identify the underlying cause and prevents complications like lung collapse or respiratory failure.
What this means
Your CA-125 level is slightly elevated above the normal range. While this can be associated with ovarian cancer, it's important to know that many benign conditions like endometriosis, fibroids, or even menstruation can cause elevations. Your doctor will likely recommend additional imaging or evaluation to determine the cause.
Recommended actions
Schedule a follow-up appointment with your gynecologist or healthcare provider to discuss these results
Your doctor may recommend pelvic ultrasound or CT imaging for further evaluation
Keep track of any symptoms like pelvic pain, bloating, or changes in your cycle
Consider retesting in 4-8 weeks to see if levels change or if this is a temporary elevation
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Sample results
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