Understanding Lab Tests for Placental Insufficiency

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Placental insufficiency is a pregnancy complication where the placenta doesn't deliver adequate oxygen and nutrients to the developing baby. While this condition is primarily diagnosed through ultrasound and other imaging studies, blood testing plays a fundamental role in monitoring placental function and assessing the risk of related complications.

Recommended Test

Estriol, LC/MS/MS, Serum

This test measures estriol levels in the blood, a hormone produced by the placenta during pregnancy. Low levels of estriol may indicate that the placenta is not functioning properly, which could lead to complications such as pre-eclampsia, slow fetal growth, or premature birth. Monitoring estriol levels helps assess placental health and guides medical management.

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Why Blood Testing is Important for Placental Function

Although there isn't a single blood test to definitively diagnose placental insufficiency, laboratory testing is essential for evaluating how well the placenta is functioning. Blood tests can measure hormones and other substances produced by the placenta, helping healthcare providers monitor pregnancy health and identify potential complications early.

Understanding the Connection

Estriol is one of the key hormones produced by a healthy placenta. When placental function is compromised, estriol production may decrease, making this test valuable for monitoring placental health throughout pregnancy. Regular monitoring can help healthcare providers make informed decisions about pregnancy management and timing of delivery if necessary.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of placental insufficiency and other pregnancy-related concerns.

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