Sample results
Placental insufficiency is a pregnancy complication where the placenta fails to deliver adequate oxygen and nutrients to the developing baby. It is caused by poor blood flow to the placenta due to maternal health conditions like preeclampsia, diabetes, high blood pressure, or abnormal placental development. The Estriol LC/MS/MS Serum test is the most important test for monitoring placental function because it measures key hormones produced by a healthy placenta.
Placental insufficiency is caused by poor blood flow to the placenta, preventing it from delivering adequate oxygen and nutrients to the baby. Maternal conditions like chronic high blood pressure, preeclampsia, diabetes, blood clotting disorders, and autoimmune diseases restrict placental blood vessels. Lifestyle factors including smoking, drug use, and advanced maternal age also damage placental tissue and reduce its ability to support fetal growth throughout pregnancy.
The Estriol LC/MS/MS Serum test is the most important blood test for monitoring placental insufficiency because it measures estriol, a hormone produced specifically by the placenta during pregnancy. Low estriol levels indicate the placenta is not functioning properly and may signal complications like preeclampsia, intrauterine growth restriction, or risk of premature birth. While ultrasound is the primary diagnostic tool for placental insufficiency, blood tests like estriol help healthcare providers monitor placental health over time and make informed decisions about pregnancy management and delivery timing.
You should get tested if your healthcare provider notices signs of poor fetal growth during prenatal visits, if you have risk factors like high blood pressure or diabetes, or if you experience decreased fetal movement in the third trimester. Women with previous pregnancy complications, autoimmune disorders, or who smoke should consider early and regular monitoring. Testing becomes especially important if ultrasounds show the baby is measuring smaller than expected for gestational age or if you develop preeclampsia symptoms like severe swelling or persistent headaches.
What this means
Your estriol level is below the typical range for this stage of pregnancy. While this may be normal for some healthy pregnancies, it could indicate that further evaluation is needed to ensure optimal fetal and placental health. Your obstetrician will interpret this result alongside your ultrasound findings and other prenatal screening results.
Recommended actions
Follow up with your obstetrician to discuss results and any additional testing needed
Ensure you're attending all scheduled prenatal appointments for comprehensive monitoring
Maintain a healthy pregnancy diet with adequate protein, healthy fats, and prenatal vitamins
Your doctor may recommend retesting in 1-2 weeks to monitor trends
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Sample results
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