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Pituitary disorders affect the pituitary gland, often called the master gland, which controls hormone production throughout the body. These disorders result from tumors, hormone deficiencies, or overproduction conditions that disrupt the balance of multiple hormone systems. The Follicle-Stimulating Hormone (FSH) test is the most important test for diagnosis because FSH levels are directly controlled by the pituitary gland.
Pituitary disorders are caused by tumors (adenomas), head injuries, infections, autoimmune conditions, or genetic mutations that affect the pituitary gland. The most common cause is a pituitary adenoma, a noncancerous tumor that can either produce excess hormones or compress the gland and reduce hormone production. Other causes include traumatic brain injury, inflammation from infections like meningitis, Sheehan syndrome after childbirth, and genetic conditions affecting pituitary development or function.
The Follicle-Stimulating Hormone (FSH) test is the most important test for pituitary disorders because it measures hormone levels directly controlled by the pituitary gland, with both elevated and decreased FSH levels indicating various types of pituitary dysfunction. Additional essential tests include the Testosterone Total LC/MS/MS to evaluate pituitary regulation of sex hormones, the Estradiol Ultrasensitive LC/MS/MS to detect subtle hormonal changes from pituitary dysfunction, and the Thyroxine Free Direct Dialysis (FT4) to assess how well the pituitary controls thyroid function through TSH production. Together, these tests provide a comprehensive evaluation of pituitary function across multiple hormone systems.
You should get tested if you experience unexplained weight changes, persistent fatigue, irregular menstrual periods or erectile dysfunction, vision problems or frequent headaches, or abnormal breast milk production. Early testing is crucial when you notice multiple symptoms affecting different body systems simultaneously, such as changes in both energy levels and reproductive function, as pituitary disorders affect multiple hormones at once. You should also get tested if you have a family history of pituitary tumors or have had head trauma or brain surgery.
What this means
Your FSH level is slightly elevated above the optimal range. In women, this may suggest diminished ovarian reserve or that your ovaries are working harder to produce eggs, which can affect fertility. In men, elevated FSH may indicate reduced testicular function or lower sperm production.
Recommended actions
Maintain a healthy weight through balanced nutrition and regular exercise
Reduce stress with meditation, yoga, or other relaxation techniques
Consider supplements like CoQ10, vitamin D, and omega-3 fatty acids after consulting with your doctor
Retest in 2-3 months and consult a fertility specialist if trying to conceive
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