Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Peritonitis is a serious inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most abdominal organs. This condition is typically diagnosed through clinical examination, imaging studies, and analysis of peritoneal fluid. While there isn't a single blood test to diagnose peritonitis directly, blood testing plays a fundamental role in monitoring the body's inflammatory response and assessing potential complications.
While primarily known as a tumor marker, CA-125 levels can become elevated during peritonitis due to the inflammatory process affecting the peritoneum. This test can help monitor the degree of peritoneal inflammation and track the body's response to treatment, providing valuable information about the severity of the condition.
Peritonitis triggers a significant inflammatory response throughout the body. Blood tests are essential for monitoring inflammation markers, tracking the progression of the condition, and evaluating treatment effectiveness. These tests help healthcare providers make informed decisions about patient care and identify any complications that may arise.
It's important to note that CA-125 elevation in peritonitis is different from its use in cancer screening. In the context of peritoneal inflammation, elevated CA-125 levels reflect the inflammatory process rather than malignancy. Healthcare providers will interpret these results alongside clinical symptoms and other diagnostic findings.
The information here is for educational purposes only and is not a substitute for professional medical advice. Peritonitis is a medical emergency requiring immediate professional care. Always consult with a healthcare provider for diagnosis and treatment.