Understanding Lab Tests for Periodontal Disease

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Periodontal disease, commonly known as gum disease, is primarily diagnosed through clinical dental examination and periodontal probing. While there is no blood test that directly diagnoses periodontal disease itself, laboratory testing plays a valuable supporting role in assessing nutritional factors that may influence gum health and healing.

Recommended Test

Coenzyme Q10(3)

This test measures blood levels of Coenzyme Q10, an important antioxidant that supports cellular energy production. Research has demonstrated that people with periodontal disease often have reduced levels of Coenzyme Q10 in their gum tissues. Testing can help identify deficiencies that may impair the body's ability to fight gum infection and promote healing.

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Why Blood Testing Can Support Periodontal Health

Research has shown that certain nutritional deficiencies and biochemical imbalances may contribute to the development or progression of periodontal disease. Blood tests can help identify these underlying factors, allowing for a more comprehensive approach to treatment and prevention that addresses both local and systemic influences on gum health.

Understanding the Connection

Coenzyme Q10 plays a crucial role in cellular metabolism and has antioxidant properties that help protect tissues from damage. When levels are insufficient, the gums may be less able to resist bacterial infection and inflammation, potentially contributing to the progression of periodontal disease. Supplementation may be beneficial when deficiencies are identified.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Regular dental care remains the primary approach for preventing and treating periodontal disease.

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