Understanding Lab Tests for Peptic Ulcer

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Peptic ulcers are open sores that develop on the inner lining of the stomach or upper portion of the small intestine (duodenum). While the diagnosis is often confirmed through imaging or endoscopy, blood tests play a crucial role in identifying underlying causes and monitoring potential complications.

Top Recommended Test

H. Pylori Antigen Stool

H. pylori is the most common bacterial cause of peptic ulcers. This test directly detects the presence of H. pylori antigens, confirming an active infection that causes inflammation and can lead to ulcer development in the stomach or duodenum lining.

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The Role of Laboratory Testing in Peptic Ulcers

Blood tests are fundamental for peptic ulcer management because they can detect the most common bacterial cause of ulcers and monitor the body's response to complications. Testing helps healthcare providers determine the appropriate treatment approach and assess overall health status.

Tests for Monitoring Complications

In some cases, peptic ulcers can lead to serious complications that affect other organs. Blood tests can help detect these complications early, allowing for prompt medical intervention.

Amylase, Serum

Peptic ulcers can potentially lead to perforation, causing leakage of pancreatic juice containing amylase into the abdominal cavity. Elevated blood amylase levels can indicate this serious complication requiring immediate medical attention.

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Lipase, Serum

The presence of peptic ulcers can trigger increased pancreatic lipase production as the body responds to the ulceration. Monitoring lipase levels helps assess pancreatic involvement and potential complications from the ulcer.

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Understanding Your Results

Test results should always be interpreted by a healthcare professional who can consider your complete medical history, symptoms, and other diagnostic findings. Early detection of H. pylori infection and monitoring for complications are essential steps in effective peptic ulcer management.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.

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