Understanding Lab Tests for Past infection of Chickenpox
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Chickenpox is a highly contagious viral infection caused by the varicella-zoster virus (VZV). While the characteristic itchy rash typically makes the diagnosis obvious during active infection, determining whether someone has had chickenpox in the past requires specific blood testing to detect antibodies produced by the immune system.
Recommended Test
Varicella-Zoster Virus (VZV) Antibodies, IgG (Chickenpox)
This blood test measures IgG antibodies specific to the varicella-zoster virus. High levels of VZV IgG antibodies indicate a past infection with chickenpox, as these antibodies remain in the body for life after infection, providing long-term immunity against the virus. This test is the gold standard for confirming previous chickenpox exposure and immunity status.
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Why Test for Past Chickenpox Infection?
Confirming previous chickenpox infection is important for several reasons: it helps establish immunity status, guides vaccination decisions, and is often required for healthcare workers, pregnant women, or individuals in certain occupations. Blood testing is the most reliable method to verify past exposure when medical history is unclear or unavailable.
Understanding Your Results
Positive IgG antibodies typically indicate immunity from either past natural infection or vaccination. However, result interpretation should always be done in consultation with a healthcare provider, who can consider your medical history and current health status when making recommendations about vaccination or other preventive measures.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
