Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Pantothenic acid deficiency, also known as Vitamin B5 deficiency, is a rare nutritional deficiency that can cause fatigue, irritability, numbness, digestive issues, and sleep disturbances. While uncommon in developed countries due to the widespread availability of this vitamin in foods, accurate diagnosis requires specific laboratory testing to measure vitamin B5 levels in the blood.
This test directly measures pantothenic acid levels in the blood to diagnose Vitamin B5 deficiency. Low levels can help explain symptoms such as fatigue, irritability, numbness, vomiting, abdominal cramps, and difficulty sleeping. While deficiency is rare in developed countries due to the broad distribution of pantothenic acid in food, this test provides definitive confirmation when deficiency is suspected.
Because the symptoms of pantothenic acid deficiency can overlap with many other conditions, a definitive diagnosis relies on blood testing that directly measures vitamin B5 levels. This testing is essential to confirm the deficiency and guide appropriate supplementation or dietary modifications.
Low pantothenic acid levels in the blood indicate a deficiency that may be contributing to your symptoms. Your healthcare provider can use these results to recommend appropriate vitamin B5 supplementation or dietary changes to restore normal levels and alleviate symptoms.
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.