Understanding Lab Tests for Panniculitis
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Panniculitis is a rare inflammatory condition affecting the subcutaneous fat layer beneath the skin, causing painful nodules and inflammation. While panniculitis is primarily diagnosed through clinical examination and sometimes tissue biopsy, blood tests play a crucial supporting role in identifying underlying causes and associated conditions.
Recommended Test
Alpha-1-Antitrypsin, Quantitative
This test measures levels of Alpha-1-Antitrypsin, an important enzyme that protects tissues from inflammation. Panniculitis can be associated with Alpha-1-Antitrypsin Deficiency, where low levels of this protective enzyme may contribute to inflammatory processes in the fatty tissue layer. Testing helps identify this potential underlying cause.
2907 reviews
The Role of Blood Testing in Panniculitis
There is no single blood test that directly diagnoses panniculitis itself. However, laboratory testing is fundamental for investigating potential underlying causes, such as enzyme deficiencies, autoimmune conditions, or systemic diseases that may trigger this inflammatory response in the fat tissue.
Understanding the Connection
Alpha-1-Antitrypsin is a protein that helps protect the body's tissues from damage caused by inflammatory enzymes. When levels are deficient, it can lead to various inflammatory conditions, including panniculitis. Identifying this deficiency is important for understanding the root cause and guiding appropriate treatment strategies.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
