Understanding Lab Tests for Paget's Disease
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Paget's disease is a chronic bone disorder that disrupts the body's normal bone recycling process, leading to enlarged, weakened, and misshapen bones. While the diagnosis of Paget's disease typically relies on imaging studies and bone biopsies, blood tests play a crucial supporting role in monitoring the disease and detecting potential complications.
Top Recommended Test
Calcium, Serum
Paget's disease is a chronic disorder that can result in enlarged and misshapen bones. In some cases, this condition can cause elevated calcium levels in the blood, particularly after a fracture or surgical procedure. Monitoring calcium levels is essential for detecting this potentially serious complication.
2907 reviews
Why Blood Testing is Important in Paget's Disease
Although there isn't a single blood test that directly diagnoses Paget's disease, laboratory testing is fundamental for assessing bone metabolism, monitoring disease activity, and checking for complications such as elevated calcium levels. These tests help healthcare providers track the body's response to the abnormal bone remodeling process characteristic of this condition.
Other Relevant Tests
Prostatic Acid Phosphatase (PAP), Serum
Although rare, elevated levels of Prostatic Acid Phosphatase (PAP) can be seen in Paget's disease, a condition that disrupts the body's normal bone recycling process. This test can help monitor disease activity and bone metabolism changes associated with the condition.
2907 reviews
Understanding Your Results
Abnormal results in these tests may indicate increased bone turnover or complications related to Paget's disease. Elevated calcium levels, in particular, can be a sign of increased bone breakdown and may require immediate medical attention. Regular monitoring helps ensure proper disease management and early detection of complications.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. Blood tests should be interpreted alongside clinical symptoms and imaging studies for comprehensive management of Paget's disease.
