Understanding Lab Tests for Orthostatic Hypotension
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Orthostatic hypotension is a condition characterized by a sudden drop in blood pressure when standing up from a sitting or lying position. The condition itself is diagnosed through blood pressure measurements, not blood tests. However, laboratory testing plays a crucial role in identifying the underlying causes that may be contributing to this blood pressure regulation problem.
Recommended Test
Catecholamines, Fractionated, Plasma (Dopamine)
This test measures levels of catecholamines, including norepinephrine, which are essential neurotransmitters for blood pressure regulation. Orthostatic hypotension can result from the body's inability to produce adequate norepinephrine in response to position changes, making this test valuable for identifying autonomic nervous system dysfunction that may be causing the blood pressure drops.
2907 reviews
Why Blood Testing is Important for Orthostatic Hypotension
While orthostatic hypotension is diagnosed by measuring blood pressure changes with position, blood tests are fundamental for investigating the root causes of the condition. The body's ability to maintain blood pressure when standing depends on complex hormonal and neurological mechanisms, and testing can reveal deficiencies or imbalances that contribute to blood pressure regulation problems.
Understanding the Connection
Normal blood pressure regulation when standing requires the release of norepinephrine and other catecholamines to constrict blood vessels and maintain adequate blood flow to the brain. When this system fails, orthostatic hypotension occurs. Testing catecholamine levels can help healthcare providers determine if autonomic nervous system dysfunction is contributing to the condition and guide appropriate treatment strategies.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
