Question 1

What is non-alcoholic fatty liver disease?

Accepted Answer

Non-alcoholic fatty liver disease (NAFLD) is a condition where excess fat accumulates in the liver of people who drink little to no alcohol. It is caused by metabolic dysfunction including insulin resistance, elevated oxidized LDL cholesterol, and increased trimethylamine N-oxide production. The Gamma Glutamyl Transpeptidase (GGT) test is the most important test for diagnosing NAFLD because it detects liver cell damage from fat accumulation.

Question 2

What causes non-alcoholic fatty liver disease?

Accepted Answer

Non-alcoholic fatty liver disease is caused by metabolic dysfunction, insulin resistance, and excess fat accumulation in liver cells. The primary drivers include elevated blood sugar levels, high triglycerides, oxidized LDL cholesterol, and obesity. Unlike alcoholic liver disease, NAFLD develops in people who drink little to no alcohol, and is strongly linked to metabolic syndrome, type 2 diabetes, and poor diet high in refined carbohydrates and saturated fats.

Question 3

What is the best test for non-alcoholic fatty liver disease?

Accepted Answer

The Gamma Glutamyl Transpeptidase (GGT) test is the most important blood test for non-alcoholic fatty liver disease because it detects liver cell damage caused by fat accumulation. When liver cells are injured, they release GGT into the bloodstream, causing elevated levels that indicate the extent of liver damage. The OxLDL test is also essential because it measures oxidized LDL cholesterol, a key contributor to fat buildup in the liver. Additionally, the TMAO test provides valuable insight into metabolic pathways that promote liver fat accumulation and disease progression.

Question 4

When should I get tested for non-alcoholic fatty liver disease?

Accepted Answer

You should get tested if you have metabolic syndrome, type 2 diabetes, or are overweight or obese, as these significantly increase your risk. Get tested if you experience unexplained fatigue, discomfort in the upper right abdomen, or have elevated liver enzymes found during routine blood work. You should also consider testing if you have high cholesterol, high triglycerides, or a family history of liver disease, even if you have no symptoms, since NAFLD often develops silently.

Question 5

What are the symptoms of non-alcoholic fatty liver disease?

Accepted Answer

Non-alcoholic fatty liver disease often causes no symptoms in its early stages, which is why many people are unaware they have it. As the condition progresses, you might experience persistent fatigue, weakness, and a dull aching or discomfort in the upper right side of your abdomen. In advanced stages, symptoms can include unexplained weight loss, loss of appetite, yellowing of the skin and eyes (jaundice), swelling in the abdomen or legs, and confusion or difficulty concentrating.

Question 6

Who is at risk for non-alcoholic fatty liver disease?

Accepted Answer

People with metabolic syndrome, type 2 diabetes, obesity, or high cholesterol are at highest risk for developing NAFLD. The condition is more common in people over age 40, though it increasingly affects younger individuals and even children with obesity. Hispanic and Asian populations have higher genetic susceptibility, while those with high triglycerides, insulin resistance, polycystic ovary syndrome (PCOS), or sleep apnea face elevated risk. A sedentary lifestyle and diet high in processed foods and sugar also significantly increase your chances of developing fatty liver disease.

Question 7

What happens if non-alcoholic fatty liver disease is left untreated?

Accepted Answer

If left untreated, non-alcoholic fatty liver disease can progress from simple fat accumulation to non-alcoholic steatohepatitis (NASH), where inflammation and liver cell damage occur. NASH can lead to liver fibrosis (scarring), which may advance to cirrhosis, a severe and irreversible condition where the liver becomes heavily scarred and loses function. Cirrhosis increases your risk of liver failure and liver cancer (hepatocellular carcinoma). NAFLD also significantly raises your risk of cardiovascular disease, heart attacks, and strokes, making early detection and management critical.

Question 8

Can non-alcoholic fatty liver disease be diagnosed with a blood test?

Accepted Answer

Blood tests cannot definitively diagnose non-alcoholic fatty liver disease on their own, but they play a crucial role in detecting liver damage and assessing risk factors. Tests like GGT, ALT, and AST measure liver enzymes that become elevated when liver cells are damaged. The OxLDL and TMAO tests identify metabolic factors contributing to fat accumulation in the liver. While imaging studies like ultrasound, FibroScan, or MRI are typically needed for definitive diagnosis, blood tests are essential for screening, monitoring disease progression, and evaluating treatment effectiveness.

Question 9

How is non-alcoholic fatty liver disease treated?

Accepted Answer

Non-alcoholic fatty liver disease is primarily treated through lifestyle modifications, with weight loss being the most effective intervention. Losing 7-10% of your body weight through a healthy diet and regular exercise can significantly reduce liver fat and inflammation. Your doctor may recommend a Mediterranean-style diet low in refined carbohydrates and saturated fats. Managing underlying conditions like diabetes, high cholesterol, and high blood pressure is essential. While no medications are specifically approved for NAFLD, your doctor may prescribe drugs to control blood sugar, cholesterol, or use vitamin E or other supplements in certain cases.

Question 10

How can I prevent non-alcoholic fatty liver disease?

Accepted Answer

You can prevent non-alcoholic fatty liver disease by maintaining a healthy weight through balanced nutrition and regular physical activity. Eat a diet rich in vegetables, fruits, whole grains, lean proteins, and healthy fats while limiting processed foods, refined sugars, and saturated fats. Exercise at least 150 minutes per week, combining aerobic activities with strength training. Control your blood sugar levels, cholesterol, and blood pressure through lifestyle and medication if needed. Avoid excessive alcohol consumption, quit smoking, and limit sugary beverages, which are strongly linked to liver fat accumulation.

Question 11

What natural remedies help with non-alcoholic fatty liver disease?

Accepted Answer

Several natural approaches can support liver health in non-alcoholic fatty liver disease. Coffee consumption (2-3 cups daily) has been shown to reduce liver inflammation and slow disease progression. Green tea contains antioxidants that may help reduce liver fat. Foods rich in omega-3 fatty acids like salmon, walnuts, and flaxseeds can decrease liver fat and inflammation. Milk thistle (silymarin) is a popular herbal supplement that may protect liver cells, though evidence is mixed. Vitamin E supplementation has shown benefits in some NAFLD patients, but consult your doctor before starting supplements. Focus on whole foods like leafy greens, berries, and foods high in fiber to naturally support liver function.

Question 12

How’s this work?

Accepted Answer

Getting your blood test with us is easy, private & backed by the power of science.Long story short:
            
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Question 13

How do I know which test to get?

Accepted Answer

In the test options, find the test you want.
            If you’re not sure which test to get, we can lend a hand in finding the right option.
            Just text or call us at 754-799-7833, email us at support@privatemdlabs.com, and we'll gladly help you. We've got your back and reply quickly.

Question 14

When will my lab results be available?

Accepted Answer

Most test results will be available within 1–3 business days. Once they're ready, we'll send an email and text message to let you know.
            After your blood draw, just hang tight and don't worry – we'll keep you updated and in the loop!
            If you have any further questions, please text us at 754-799-7833 or email support@privatemdlabs.com, and we'll gladly help you.

Question 15

Is it possible to make changes to my lab order if I made a mistake with the name, date of birth, or any other details?

Accepted Answer

Absolutely! We totally understand that errors can happen. No worries, we're here to help you.
            Just reach out to us via text at 754-799-7833 or shoot us an email at
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            There are no changes necessary if your address is wrong on the requisition though. We don’t mail anything out.
            Our lab requires an address to be listed to generate an order.

Question 16

Do you accept health insurance?

Accepted Answer

Only HSA & FSA is accepted.
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Question 17

Can I cancel my order?

Accepted Answer

Yes.
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Question 18

How can I find a lab location near me?

Accepted Answer

During the ordering process, you’ll be able to select a specific lab near you, with no strings attached!
            You can switch it up later easily and visit any of our authorized locations as long as it’s the same lab company you selected your test for (Quest Diagnostics or Labcorp).
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            If you have any questions, please text us at 754-799-7833 or email support@privatemdlabs.com and we'll gladly help you.

Fatty Liver Disease Blood Test

What is Non-alcoholic Fatty Liver Disease?

What causes non-alcoholic fatty liver disease?

What is the best test for non-alcoholic fatty liver disease?

When should I get tested for non-alcoholic fatty liver disease?

References

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