Understanding Lab Tests for Neuropathy
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Neuropathy refers to damage or dysfunction of nerves, causing symptoms like tingling, numbness, weakness, and pain, typically in the hands and feet. While neuropathy is primarily diagnosed through clinical examination and nerve function tests, blood tests play a crucial role in identifying underlying causes and contributing factors.
Top Recommended Test
Vitamin B12
This test measures vitamin B12 levels in the blood. Vitamin B12 deficiency is one of the most common and treatable causes of peripheral neuropathy. Low levels can lead to significant nerve damage, causing characteristic symptoms like tingling and numbness in the extremities.
2907 reviews
Why Blood Testing is Important for Neuropathy
There isn't a single blood test to diagnose neuropathy itself, but lab testing is fundamental for uncovering treatable causes. Many cases of neuropathy result from nutritional deficiencies, metabolic disorders, or immune responses that can be detected through blood work. Identifying these underlying factors is essential for proper treatment and potentially reversing nerve damage.
Other Relevant Tests
Vitamin B12 and Folates
This comprehensive test evaluates both vitamin B12 and folate levels. Deficiencies in these B vitamins can cause nerve damage leading to neuropathy symptoms including tingling, numbness in hands and feet, and balance problems. This test provides a broader assessment of nutritional factors that may be contributing to nerve dysfunction.
2907 reviews
Diphtheria and Tetanus Antitoxoid
This test measures antibody levels against diphtheria and tetanus. In very rare cases, vaccines that stimulate production of these antitoxoids can trigger an immune response leading to neuropathy. This test can help determine if recent vaccination might be related to nerve symptoms, though this is an extremely uncommon cause of neuropathy.
2907 reviews
Understanding Your Results
Blood test results for neuropathy evaluation should always be interpreted by a healthcare provider who can correlate findings with your symptoms and medical history. Identifying treatable causes like vitamin deficiencies can significantly improve outcomes and potentially prevent further nerve damage.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.
