Understanding Lab Tests for Neural Tube Defects in Fetus
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Neural tube defects are serious birth defects that affect the brain, spine, or spinal cord, including conditions like spina bifida and anencephaly. These defects are typically diagnosed through prenatal imaging and screening tests during pregnancy, not through blood tests alone. However, blood testing plays a crucial role in prevention and risk assessment.
Recommended Test
Folate, RBC
This test measures folate levels stored in red blood cells, providing a more accurate picture of long-term folate status compared to serum folate. Low folate levels in pregnant women are strongly linked to increased risk of neural tube defects in the developing fetus. Monitoring and maintaining adequate folate levels is essential for prevention of conditions like spina bifida and anencephaly.
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The Role of Blood Testing in Prevention
While there is no single blood test to diagnose neural tube defects in a developing fetus, blood testing is fundamental for assessing nutritional factors that significantly influence the risk of these defects. Adequate folate levels before conception and during early pregnancy are critical for proper neural tube development.
Prevention and Early Intervention
Testing folate levels allows healthcare providers to identify deficiencies early and recommend appropriate supplementation. This is particularly important for women planning pregnancy or in early pregnancy, as neural tube development occurs very early in fetal development, often before a woman knows she is pregnant.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for proper prenatal care, diagnosis, and treatment recommendations.
