Understanding Lab Tests for Neonatal Jaundice

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Neonatal jaundice is a common condition that affects many newborns, characterized by the yellowing of the skin and whites of the eyes. This occurs due to elevated levels of bilirubin in the blood, often because a newborn's liver is not yet mature enough to efficiently process and eliminate this substance.

Top Recommended Test

Bilirubin, Total

This is the primary diagnostic test for neonatal jaundice. It directly measures the total amount of bilirubin in the blood, which accumulates when a newborn's immature liver cannot efficiently process and eliminate this substance. Elevated levels confirm the presence and severity of jaundice.

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Why Blood Testing is Essential for Neonatal Jaundice

While jaundice can often be observed visually, blood tests are fundamental for accurately measuring bilirubin levels, determining the severity of the condition, and identifying underlying causes. These tests guide healthcare providers in deciding whether treatment is necessary and help monitor the baby's progress.

Other Relevant Tests

Glucose-6-Phosphate Dehydrogenase Quantitative

This test checks for G6PD deficiency, an important underlying cause of neonatal jaundice. When this enzyme is deficient, red blood cells break down more easily, leading to increased bilirubin production and more severe jaundice. Identifying this deficiency helps explain why jaundice occurred and guides appropriate treatment.

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Understanding Your Results

Bilirubin levels help determine if the jaundice is within normal ranges or if intervention is needed. The G6PD test can reveal if an enzyme deficiency is contributing to the condition. Both tests together provide a comprehensive picture for managing your baby's health.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of neonatal jaundice.

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