Understanding Lab Tests for Neonatal Hepatitis and Jaundice
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Neonatal hepatitis and jaundice are serious conditions affecting newborns, characterized by liver inflammation and yellowing of the skin and eyes. While diagnosis involves clinical examination and imaging, blood tests are fundamental for identifying underlying genetic causes, assessing liver function, and monitoring the severity of the condition.
Recommended Test
Alpha-1-Antitrypsin, Quantitative
This test measures the level of alpha-1-antitrypsin protein in the blood. Alpha-1-Antitrypsin Deficiency is a genetic condition that can cause neonatal hepatitis and jaundice in newborns. When this protein is deficient or abnormal, it can accumulate in liver cells, leading to liver inflammation and damage. Testing helps identify this specific genetic cause of neonatal liver disease.
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Why Blood Testing is Essential
Neonatal hepatitis and jaundice can have various causes, including genetic disorders, infections, and metabolic conditions. Blood tests help healthcare providers determine the specific underlying cause, evaluate how well the liver is functioning, and guide appropriate treatment strategies to prevent long-term complications.
Understanding the Results
Low levels of alpha-1-antitrypsin may indicate a deficiency that could be contributing to the newborn's liver problems. Early identification of this genetic condition is crucial as it allows for appropriate monitoring and management to prevent further liver damage and potential complications affecting both liver and lung function later in life.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Neonatal hepatitis and jaundice require immediate medical attention and comprehensive evaluation by pediatric specialists. Always consult with a healthcare provider for diagnosis and treatment.
