Myalgia and myositis are conditions characterized by muscle pain and inflammation that can severely limit daily activities. Myositis is often caused by autoimmune processes where the body attacks its own muscle tissue, with specific antibodies like cytosolic 5'-nucleotidase 1A (cN-1A) indicating autoimmune muscle disease. The Cytosolic 5'-Nucleotidase 1A (cN-1A) Antibody (IgG) test is the most important test for diagnosing autoimmune myositis.
90-day money-back guarantee
Lab order in minutes
Save a trip to the doctor
Low prices since 2005
Labs within 2 miles
Myalgia and myositis are caused by different mechanisms depending on the type. Myalgia can result from muscle overuse, viral infections like influenza, stress, or medications like statins. Myositis is primarily caused by autoimmune processes where the immune system mistakenly attacks muscle tissue, producing antibodies such as cN-1A that target muscle cells. Other causes include inflammatory conditions, certain medications, and rarely, infections or cancers that trigger immune responses against muscle tissue.
The Cytosolic 5'-Nucleotidase 1A (cN-1A) Antibody (IgG) test is the most important test for diagnosing autoimmune myositis because it detects specific antibodies that indicate your immune system is attacking muscle tissue. This specialized blood test identifies cN-1A antibodies that are directly associated with inflammatory muscle disease, helping distinguish autoimmune myositis from simple muscle pain. Elevated cN-1A antibody levels confirm the diagnosis and help your doctor determine whether you need immunosuppressive treatment or corticosteroids to manage the autoimmune inflammation.
You should get tested if you experience persistent muscle pain that does not improve with rest, unexplained muscle weakness that affects daily activities like climbing stairs or lifting objects, muscle tenderness or swelling without injury, fatigue accompanied by muscle aching, or if you have difficulty swallowing or breathing due to muscle weakness. Testing is especially important if your muscle symptoms appeared suddenly, are progressively worsening, or are accompanied by rashes or other autoimmune symptoms, as early diagnosis of autoimmune myositis leads to better treatment outcomes.
Save a trip to the doctor, go directly to the lab
Instant orders, results often overnight*
Results explained in simple language
Reviewed by US licensed doctors
Fast & confidential, we never sell or share your data
No insurance needed, transparent pricing
What this means
Your test came back negative, meaning no cN-1A antibodies were detected in your blood. This result makes inclusion body myositis less likely, though it doesn't completely rule it out since some people with IBM test negative. If muscle weakness persists, your doctor may recommend additional tests or evaluation.
Recommended actions
Discuss your ongoing symptoms with a neurologist or rheumatologist
Consider additional muscle testing such as EMG or muscle biopsy if symptoms continue
Maintain muscle strength through gentle physical therapy and regular movement
Keep a symptom diary to track any progression or changes in weakness patterns
Not overhyped or overpriced. Just comprehensive blood testing made simple and for everyone.
3303 reviews
Sample results
Your 24/7 Personal Lab Guide
Quick questions:
