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Multiple pregnancy occurs when a woman carries two or more babies simultaneously, such as twins, triplets, or higher-order multiples. It is caused by either the fertilization of multiple eggs (fraternal) or the splitting of a single fertilized egg (identical). The Pregnancy Test (Very Early) - Human Chorionic Gonadotropin (hCG), Total, Quantitative is the most important blood test for early detection because significantly elevated hCG levels can indicate the presence of multiple fetuses.
Multiple pregnancy is caused by either hyperovulation (releasing multiple eggs during one cycle) or the spontaneous splitting of a single fertilized embryo. Fraternal twins or triplets occur when two or more eggs are fertilized by separate sperm, while identical multiples result from one fertilized egg dividing into two or more embryos. Factors that increase the likelihood include fertility treatments, family history of twins, maternal age over 30, and having previous pregnancies.
The Pregnancy Test (Very Early) - Human Chorionic Gonadotropin (hCG), Total, Quantitative is the most important blood test for early detection of multiple pregnancy because it measures precise hCG hormone levels in your blood. Women carrying twins, triplets, or more typically have hCG levels that are significantly higher than the expected range for single pregnancies, often 30-50% higher or more. This occurs because each placenta produces hCG, so more babies means more placental tissue and dramatically elevated hormone levels. While this blood test provides crucial early indicators, your healthcare provider will confirm multiple pregnancy with ultrasound imaging, which can visualize the number of fetuses and placentas.
You should get tested if you used fertility treatments like IVF or ovulation-inducing medications, have a family history of twins, experience unusually severe morning sickness, or notice your belly growing faster than expected for your gestational age. Early testing is especially important if you have extreme fatigue, very tender breasts, or if an at-home pregnancy test shows an unusually dark positive line very early. Women over 35 or those who have had multiple previous pregnancies should also consider early testing, as these factors increase the likelihood of releasing multiple eggs.
What this means
Your hCG test is positive, confirming pregnancy. Your level of 125 mIU/mL is consistent with very early pregnancy, typically around 4-5 weeks from your last menstrual period. In a healthy pregnancy, hCG levels should approximately double every 48-72 hours during the first few weeks.
Recommended actions
Schedule your first prenatal appointment with an OB-GYN within the next 1-2 weeks
Begin taking prenatal vitamins with folic acid if you haven't already
Avoid alcohol, smoking, and certain medications - consult your doctor about any current medications
Consider retesting in 48-72 hours to confirm hCG levels are rising appropriately
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