Understanding Lab Tests for Monocytopenia

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Monocytopenia is a blood condition characterized by abnormally low levels of monocytes, a type of white blood cell that plays a crucial role in the immune system. Monocytes help fight infections and remove damaged cells from the body. When their levels drop below normal, it can increase susceptibility to infections.

Recommended Test

Complete Blood Count / CBC (includes Differential and Platelets)

This comprehensive blood test is the primary diagnostic tool for detecting monocytopenia. The CBC with differential provides a detailed count of all white blood cell types, including monocytes. Low monocyte levels identified through this test can indicate monocytopenia, a condition that may increase the risk of infections. The test can also help identify if the condition is related to certain infections or treatments such as chemotherapy.

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Diagnosing Monocytopenia

Monocytopenia is diagnosed through blood testing that measures the specific levels of different white blood cell types, including monocytes. This condition can result from various causes including certain infections, autoimmune disorders, medications like chemotherapy, or bone marrow problems. Early detection through proper testing is essential for identifying the underlying cause and preventing complications.

Understanding Your Results

Normal monocyte levels typically range from 2% to 10% of total white blood cells, or about 200-1000 cells per microliter of blood. Values below this range may indicate monocytopenia. Your healthcare provider will interpret your results in the context of your symptoms, medical history, and other blood cell counts to determine the appropriate course of action.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment. If you have symptoms of frequent infections or other immune system concerns, discuss CBC testing with your doctor.

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