Mold allergy is an immune system overreaction to mold spores found indoors and outdoors. It is caused by exposure to common mold species including Alternaria alternata, Aspergillus fumigatus, Cladosporium herbarum, and Penicillium notatum. The Respiratory Allergy Profile is the most important test for diagnosis because it measures specific IgE antibodies to identify which mold allergens trigger your symptoms.
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Mold allergy is caused by your immune system overreacting to mold spores from species like Alternaria alternata, Aspergillus fumigatus, Cladosporium herbarum, and Penicillium notatum. When you breathe in these microscopic spores, your body produces immunoglobulin E (IgE) antibodies that trigger allergic reactions. These molds are present year-round both indoors in damp areas like basements and bathrooms, and outdoors in soil, compost, and decaying vegetation, making exposure difficult to avoid completely.
The Respiratory Allergy Profile is the most important test for mold allergy because it measures specific IgE antibodies to identify exactly which mold species trigger your symptoms. For California Central Valley residents, the Respiratory Allergy Profile Region XIV tests for Alternaria alternata, Aspergillus fumigatus, Cladosporium herbarum, and Penicillium notatum. For those in Georgia, northern Florida, and South Carolina, the Respiratory Allergy Panel Region III detects IgE antibodies to common southeastern molds including Penicillium notatum. These regional panels provide targeted results based on the molds you are most likely to encounter in your specific geographic area, helping your doctor create an effective treatment plan.
You should get tested if you experience persistent sneezing, runny nose, nasal congestion, or itchy eyes that worsen in damp environments or during humid weather. Get tested if your symptoms flare up when you are in basements, bathrooms, or areas with visible mold growth, or if over-the-counter allergy medications are not providing relief. Testing is especially important if you have asthma that worsens with respiratory symptoms, as mold allergies can trigger serious asthma attacks and knowing your specific triggers helps you avoid dangerous exposures.
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What this means
Your total IgE level is elevated, which indicates your immune system is actively responding to allergens in your environment. This is common in people with respiratory allergies and suggests you're sensitized to one or more of the allergens tested in this panel. Elevated IgE often correlates with symptoms like sneezing, congestion, and itchy eyes.
Recommended actions
Review your specific allergen results to identify your primary triggers
Implement environmental controls like HEPA filters and allergen-proof bedding
Consider starting antihistamines during peak allergy seasons in the Central Valley
Retest annually or after implementing allergy management strategies to track improvement
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