Understanding Lab Tests for Miscarriage or Fetal Death
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Miscarriage or fetal death is typically diagnosed through ultrasound examination and clinical assessment. While there is no single blood test to diagnose pregnancy loss itself, laboratory testing plays a fundamental role in investigating potential underlying causes, especially for women who have experienced recurrent pregnancy losses.
Recommended Test
Cardiolipin Antibodies (IgA, IgG, IgM)
This test measures antibodies that can increase the risk of blood clots in placental vessels, potentially leading to recurrent miscarriages or fetal deaths. Elevated levels, particularly of IgG and IgM antibodies, indicate an autoimmune condition that may interfere with normal blood flow to the developing fetus. Identifying these antibodies is crucial as this condition can often be managed with appropriate medical treatment.
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Why Blood Testing is Important
When pregnancy loss occurs repeatedly, blood tests become essential for identifying treatable conditions that may contribute to these tragic outcomes. Testing helps healthcare providers develop targeted treatment plans to improve the chances of successful future pregnancies by addressing underlying medical conditions.
When Testing May Be Recommended
Healthcare providers typically recommend cardiolipin antibody testing for women who have experienced two or more pregnancy losses, particularly when losses occur in the second trimester or later. Early identification and treatment of elevated cardiolipin antibodies may help prevent future pregnancy complications.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis, treatment, and guidance regarding pregnancy loss and fertility concerns.
