Understanding Lab Tests for Metastatic Cancers in the Liver
Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Metastatic cancers in the liver occur when cancer cells from other parts of the body spread to the liver. While imaging studies are typically used to diagnose liver metastases, blood tests play a crucial role in monitoring disease progression, assessing treatment response, and tracking tumor activity.
Recommended Test
Alpha-Fetoprotein (AFP), Serum, Tumor Marker
This test measures AFP levels in the blood, which can become elevated when metastatic cancers spread to the liver. Tumor cells in the liver may produce and release AFP, making this test valuable for monitoring disease progression, assessing treatment response, and tracking cancer activity over time.
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The Role of Blood Testing in Liver Metastases
Although there isn't a single blood test that can definitively diagnose metastatic liver cancer, tumor marker testing is fundamental for monitoring cancer activity and treatment effectiveness. Certain cancers that metastasize to the liver can produce specific proteins that can be detected in the blood, providing valuable information about disease status.
Understanding Your Results
Elevated AFP levels may indicate active cancer in the liver, but results must be interpreted alongside other clinical findings and imaging studies. Regular monitoring of tumor markers helps healthcare providers adjust treatment plans and assess how well therapy is working.
Important Considerations
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of metastatic cancer.
