Metabolic disorders are conditions that disrupt the body's ability to process nutrients, maintain chemical balance, or produce energy. They are caused by enzyme deficiencies, hormonal imbalances, electrolyte disturbances, or organ dysfunction affecting metabolic pathways. The Comprehensive Metabolic Profile is the most important test for diagnosis because it measures critical markers including carbon dioxide, electrolytes, glucose, and kidney function.
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Metabolic disorders are caused by enzyme deficiencies, hormonal imbalances, electrolyte disturbances, or organ dysfunction that disrupts normal biochemical processes. Some metabolic disorders are inherited genetic conditions where your body lacks specific enzymes needed to break down nutrients, while others develop from diseases affecting organs like the kidneys, liver, or pancreas. For example, diabetes results from insufficient insulin production or insulin resistance, while metabolic acidosis occurs when the kidneys fail to eliminate enough acid or the body produces excessive acid from conditions like diabetic ketoacidosis or kidney disease.
The Comprehensive Metabolic Profile is the most important test for metabolic disorders because it detects critical imbalances in electrolytes, glucose, carbon dioxide, and kidney function markers. This panel specifically measures carbon dioxide levels, which when low can indicate metabolic acidosis where your body produces too much acid or cannot eliminate it properly. The test also evaluates sodium, potassium, chloride, calcium, blood glucose, blood urea nitrogen (BUN), creatinine, and liver enzymes, providing a complete picture of your metabolic health. These markers reveal dysfunction in multiple organ systems and help identify conditions like diabetes, kidney disease, liver problems, and dangerous acid-base imbalances that require immediate medical attention.
You should get tested if you experience unexplained fatigue, excessive thirst or urination, confusion, muscle weakness, irregular heartbeat, or rapid breathing. Testing is also important if you have risk factors like diabetes, kidney disease, liver problems, or a family history of metabolic conditions. Get immediate testing if you develop severe symptoms like persistent vomiting, extreme confusion, shortness of breath, or chest pain, as these can indicate serious metabolic emergencies like diabetic ketoacidosis or severe electrolyte imbalances that require urgent treatment.
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What this means
Your eGFR is slightly below the optimal range, indicating your kidneys may not be filtering waste as efficiently as they should. This could be an early sign of reduced kidney function that warrants closer monitoring and lifestyle adjustments to prevent further decline.
Recommended actions
Stay well-hydrated by drinking plenty of water throughout the day
Reduce sodium intake and limit processed foods to ease kidney workload
Maintain healthy blood pressure through diet, exercise, and stress management
Retest in 3-6 months to monitor kidney function trends
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