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Liver injury is damage to liver cells caused by medications, toxins, infections, alcohol, or physical trauma. It occurs when hepatocytes (liver cells) become inflamed or die, releasing enzymes like alanine aminotransferase (ALT) and aspartate aminotransferase (AST) into the bloodstream. The Liver Function Profile is the most important test for diagnosing liver injury because it measures these specific liver enzymes.
Liver injury is caused by medications like acetaminophen and statins, excessive alcohol consumption, viral infections such as hepatitis B and hepatitis C, environmental toxins, fatty liver disease, and autoimmune conditions. Acetaminophen overdose is one of the most common causes of acute liver injury in the United States. When liver cells are damaged by these factors, they release enzymes into your bloodstream that can be detected through blood tests.
The Liver Function Profile is the most important test for liver injury because it measures critical liver enzymes including ALT (alanine aminotransferase), AST (aspartate aminotransferase), alkaline phosphatase, and bilirubin levels. ALT is particularly sensitive to liver cell damage and elevated levels directly indicate active liver injury or inflammation. This comprehensive panel also assesses how well your liver is producing proteins like albumin and processing waste products, giving your healthcare provider a complete picture of your liver health and the severity of any damage.
You should get tested if you experience yellowing of your skin or eyes (jaundice), persistent fatigue, dark urine, pale stools, abdominal pain in the upper right side, unexplained nausea or vomiting, or if you take medications known to affect the liver. Testing is also important if you have been exposed to hepatitis, consume alcohol regularly, or have been using acetaminophen or other medications at high doses. Early detection through blood work can prevent serious complications and help your doctor adjust treatments before permanent liver damage occurs.
What this means
Your ALT level is slightly elevated above the optimal range, which may indicate mild liver inflammation or stress. This is commonly seen with fatty liver, alcohol use, certain medications, or metabolic conditions, and while not immediately alarming, it suggests your liver could benefit from some extra support.
Recommended actions
Reduce or eliminate alcohol consumption and limit processed foods
Incorporate regular exercise and work toward a healthy weight if needed
Increase intake of liver-supporting foods like leafy greens, beets, and cruciferous vegetables
Retest in 3-6 months to monitor improvement after lifestyle changes
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