Understanding Lab Tests for Lactose Intolerance

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Lactose intolerance is a digestive condition where the body cannot properly break down lactose, a sugar found in milk and dairy products. This occurs due to insufficient production of lactase, an enzyme needed to digest lactose. While lactose intolerance is typically diagnosed through clinical symptoms and dietary elimination, blood tests can provide valuable insights into related immune responses and enzyme deficiencies.

Top Recommended Test

Allergen Specific IgE Lactase

This test measures IgE antibodies specific to lactase and helps determine if a person has a lactase deficiency that could be causing lactose intolerance symptoms. It provides direct insight into the body's ability to produce the enzyme necessary for lactose digestion.

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The Role of Blood Testing in Lactose Intolerance

There isn't a single standard blood test that directly diagnoses lactose intolerance. However, specialized blood tests are fundamental for distinguishing between lactose intolerance and dairy protein allergies, identifying lactase enzyme deficiency, and understanding immune responses to specific milk proteins. These tests help healthcare providers develop appropriate dietary recommendations and treatment plans.

Other Relevant Tests

Whey (f236) IgG

This test measures IgG antibodies to whey protein and can indicate an overall intolerance to dairy products. While not directly causing lactose intolerance, elevated levels help differentiate between lactose intolerance and whey protein sensitivity, providing a clearer picture of dairy-related digestive issues.

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$121

Beta lactoglobulin (f77) IgG

This test detects IgG antibodies to beta lactoglobulin, a specific milk protein. Some individuals with lactose intolerance may also produce immune responses to milk proteins, and this test helps identify whether symptoms are due to lactase deficiency alone or combined with protein sensitivities.

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$120

Understanding Your Results

These blood tests help distinguish between different types of dairy-related digestive issues. Lactose intolerance involves enzyme deficiency, while dairy protein allergies involve immune system responses. Understanding these differences is crucial for proper dietary management and symptom relief.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for proper diagnosis and treatment of digestive concerns.

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