Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Kidney failure, also known as renal failure, occurs when the kidneys lose their ability to filter waste and excess fluids from the blood effectively. While kidney failure is primarily diagnosed through blood tests measuring creatinine and blood urea nitrogen (BUN), additional specialized testing is crucial for identifying underlying causes and preventing further kidney damage.
This specialized urine test detects ethylene glycol, a toxic substance found in antifreeze and other industrial products. Chronic exposure to ethylene glycol through ingestion or prolonged skin contact can cause severe kidney damage and failure due to toxic metabolite buildup. Testing for ethylene glycol in urine helps identify this potentially treatable cause of kidney dysfunction, allowing for prompt intervention to prevent further damage.
Beyond standard kidney function tests, specialized laboratory testing plays a vital role in identifying potential toxic exposures that may be contributing to kidney damage. Detecting and eliminating these toxic substances is essential for preventing progression of kidney failure and protecting remaining kidney function.
Healthcare providers may recommend ethylene glycol testing when kidney failure occurs in individuals with potential exposure to antifreeze, coolants, or industrial chemicals, especially if the cause of kidney damage is unclear. Early detection of toxic exposure can be critical for treatment decisions and preventing additional kidney damage.
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of kidney failure.