Insulinoma is a rare tumor of the pancreas that produces excessive amounts of insulin, leading to dangerously low blood sugar levels. It is caused by abnormal growth of insulin-producing beta cells in the pancreas that continuously secrete insulin regardless of blood glucose levels. The Insulin, Fasting test is the most important test for diagnosis because it detects inappropriately high insulin levels during hypoglycemic episodes.
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Insulinoma is caused by abnormal growth of insulin-producing beta cells in the pancreas that form a tumor. These tumors continuously secrete excessive amounts of insulin, regardless of your blood sugar levels. Most insulinomas are benign (non-cancerous) and occur as single tumors, though in rare cases they can be part of a genetic condition called multiple endocrine neoplasia type 1 (MEN1).
The Insulin, Fasting test is the most important test for insulinoma because it measures insulin levels during fasting conditions when insulin should be low. Insulinomas produce excess insulin even when blood sugar drops, so finding inappropriately high fasting insulin alongside low blood glucose is a key diagnostic marker. The C-Peptide, Serum test is essential as a companion test because it confirms the insulin is coming from your pancreas rather than from injected insulin. The Proinsulin test provides additional confirmation, as insulinomas often release disproportionately high amounts of proinsulin compared to normal pancreatic cells.
You should get tested if you experience repeated episodes of low blood sugar symptoms that improve after eating, especially if they occur when fasting or before meals. Warning signs include shakiness, sweating, confusion, rapid heartbeat, dizziness, blurred vision, or fainting spells that happen in the morning or several hours after eating. You should also consider testing if you have unexplained weight gain from eating frequently to prevent low blood sugar symptoms, or if you have a family history of multiple endocrine neoplasia type 1 (MEN1).
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What this means
Your fasting insulin level is elevated above the optimal range, which suggests early insulin resistance. This means your body is producing extra insulin to maintain normal blood sugar levels, often occurring years before prediabetes develops. This is a valuable early warning sign that gives you time to make preventive changes.
Recommended actions
Reduce refined carbs and sugar; focus on whole foods, lean proteins, and fiber-rich vegetables
Add 30 minutes of walking after meals and incorporate strength training 2-3 times per week
Prioritize 7-8 hours of quality sleep and manage stress through meditation or yoga
Retest in 3-6 months to track progress after implementing lifestyle changes
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