Infectious diseases are illnesses caused by pathogenic microorganisms including bacteria, viruses, parasites, or fungi that invade the body. They are caused by specific pathogens such as Streptococcus bacteria, influenza virus, Plasmodium parasites, or Candida fungi that trigger immune responses. The IgG, IgA Indirect Immunofluorescence test is the most important test for diagnosis because it detects specific antibody responses to these infectious agents.
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Infectious diseases are caused by pathogenic microorganisms that invade and multiply in the body. Bacteria like Streptococcus and Staphylococcus aureus, viruses such as influenza and HIV, parasites including Plasmodium (malaria) and Giardia, and fungi like Candida albicans are common infectious agents. These pathogens enter the body through various routes including respiratory droplets, contaminated food or water, insect bites, or direct contact with infected individuals. Once inside, they trigger immune responses as your body attempts to fight off the invaders, leading to inflammation and the characteristic symptoms of infection.
The IgG, IgA Indirect Immunofluorescence test is the most important test for infectious diseases because it detects specific antibodies your immune system produces in response to viral, bacterial, and parasitic infections. This comprehensive test identifies both IgG antibodies, which indicate past exposure or immunity and can persist for months to years, and IgA antibodies, which signal recent or active infections and are particularly important for mucosal immunity. The indirect immunofluorescence technique provides highly specific results by using fluorescent markers to identify antibody-antigen reactions, allowing for accurate diagnosis of various infectious agents when the pathogen itself is difficult to detect directly.
You should get tested if you experience persistent fever lasting more than a few days, unexplained fatigue or weakness, recurring infections, night sweats, or symptoms that don't improve with standard treatment. Testing is also important if you have been exposed to someone with a known infection, have recently traveled to areas with endemic diseases, or have a weakened immune system due to conditions like diabetes or HIV. Early detection through blood testing helps identify the specific pathogen causing your symptoms, allowing for targeted treatment and preventing potential complications or transmission to others.
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What this means
Your test came back negative, meaning no anti-epithelial cell surface antibodies were detected in your blood. This is the expected and healthy result, suggesting no active autoimmune blistering disease affecting the connections between skin cells.
Recommended actions
Continue monitoring any skin symptoms and report new blistering to your doctor
Maintain good skin care practices and protect skin from excessive friction
If you develop unexplained blisters or sores, consider retesting
Follow up with your dermatologist if symptoms persist despite negative results
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