Immune system disorders are conditions where the body's immune response is weakened, overactive, or misdirected against its own tissues. These disorders are caused by nutritional deficiencies like selenium, genetic mutations, autoimmune processes, or chronic infections that compromise immune function. The Selenium 24-Hour Urine test is the most important test for evaluating immune system health because selenium is essential for proper immune cell function and antioxidant defense.
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Immune system disorders are caused by genetic mutations, nutritional deficiencies like selenium or zinc, autoimmune reactions where the body attacks itself, chronic viral or bacterial infections, and environmental toxins that damage immune cells. Selenium deficiency specifically weakens the function of T-cells and natural killer cells that fight infections. Some people are born with primary immunodeficiency disorders from inherited genetic defects, while others develop secondary immunodeficiency from conditions like HIV, cancer treatments, or chronic stress that suppress immune function over time.
The Selenium 24-Hour Urine test is the most important test for immune system disorders because it measures selenium levels, which are essential for proper immune cell function and antioxidant defense against cellular damage. Selenium deficiency impairs the production and activity of immune cells including T-lymphocytes and natural killer cells that protect against infections and cancer. This 24-hour urine collection provides the most accurate assessment of your body's selenium status compared to blood tests, helping identify whether low selenium could be contributing to frequent infections, slow wound healing, or autoimmune symptoms. Correcting selenium deficiency through diet or supplementation can significantly improve immune function in people with compromised immunity.
You should get tested if you experience frequent infections like colds, flu, sinus infections, or pneumonia more than 4-6 times per year, if infections are severe or take unusually long to clear up, or if you have persistent fatigue and inflammation despite rest. Testing is also important if you have unexplained weight changes, chronic digestive issues, or a family history of autoimmune conditions like lupus, rheumatoid arthritis, or thyroid disease. If you notice wounds healing slowly, have recurring yeast infections or skin rashes, or feel generally run-down with swollen lymph nodes, checking your selenium and other immune markers can identify nutritional deficiencies affecting your immunity.
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What this means
Your 24-hour urine selenium level is below the optimal range, indicating your body may not be getting enough of this essential mineral. This deficiency can contribute to fatigue, weakened immune function, and suboptimal thyroid performance, as selenium plays a critical role in all these areas.
Recommended actions
Add 2-3 Brazil nuts daily to your diet, which are extremely rich in selenium
Include more selenium-rich foods like seafood, eggs, chicken, and whole grains
Ensure proper digestive health to optimize selenium absorption
Retest in 8-12 weeks after making dietary changes to monitor improvement
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