Understanding Lab Tests for Immune Deficiency

Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025

Immune deficiency occurs when the immune system is weakened or unable to function properly, making individuals more susceptible to infections and diseases. While there isn't a single blood test that definitively diagnoses all forms of immune deficiency, specific antibody tests are fundamental for evaluating immune system function and identifying potential deficiencies.

Top Recommended Test

Measles Antibody (IgG)

This test measures IgG antibodies against measles virus. Low or absent levels of measles antibodies after vaccination or previous infection may indicate an immune deficiency, as a normally functioning immune system should produce and maintain protective antibody levels. This test helps evaluate whether the immune system has responded appropriately to measles exposure or vaccination.

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How Blood Tests Help Assess Immune Function

Blood tests can measure the body's antibody response to common infections or vaccines. When the immune system is functioning normally, it produces antibodies (IgG) after vaccination or infection that provide long-term protection. Low or absent antibody levels may indicate that the immune system is not responding appropriately, suggesting a possible immune deficiency.

Other Relevant Tests

Mumps Virus Antibody (IgG)

This test measures IgG antibodies against mumps virus. Low levels of mumps antibodies could indicate an immune deficiency where the body's immune system is not responding properly to the virus or vaccination. Poor immune status can increase susceptibility to infections like mumps, and this test helps assess the immune system's ability to maintain protective immunity.

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Understanding Your Results

These antibody tests provide valuable information about immune system function by measuring the body's response to common pathogens. However, immune deficiency can have various underlying causes, including genetic factors, medical conditions, medications, or aging. A healthcare provider can interpret these results in the context of your overall health and medical history.

Important Considerations

The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for proper diagnosis and treatment of immune deficiency concerns.

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