Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
IgA vasculitis, formerly known as Henoch-Schönlein purpura, is an inflammatory disorder affecting small blood vessels throughout the body. While the diagnosis is primarily based on clinical symptoms and physical examination findings, blood tests play a crucial supporting role in evaluation and monitoring.
This test measures the levels of immunoglobulin A (IgA) in the blood. In IgA vasculitis, elevated IgA levels may be present as this antibody builds up in small blood vessels, causing inflammation and the characteristic symptoms of the condition. Monitoring IgA levels helps assess disease activity and response to treatment.
There is no single blood test that definitively diagnoses IgA vasculitis. However, laboratory testing is fundamental for assessing the underlying immune system activity, monitoring disease progression, and ruling out other conditions with similar symptoms. Blood tests help healthcare providers understand the body's inflammatory response and guide treatment decisions.
IgA vasculitis occurs when IgA antibodies deposit in the walls of small blood vessels, triggering an inflammatory response. This can affect the skin, joints, gastrointestinal tract, and kidneys. While the characteristic purple rash and other clinical features are key to diagnosis, measuring blood IgA levels provides valuable information about the immune system's involvement in the disease process.
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment of IgA vasculitis or any other medical condition.