Written by Private MD Labs Medical Writing Team • Last Updated: September 8, 2025
Hypoproteinemia is a medical condition characterized by abnormally low levels of protein in the blood. This condition can result from various underlying causes including malnutrition, liver disease, kidney disease, or other conditions that affect the body's ability to produce or retain proteins. Accurate diagnosis requires specific blood testing to measure protein levels.
This test directly measures the total amount of protein in the blood serum, which is the primary diagnostic marker for hypoproteinemia. Low total protein levels in the blood confirm the presence of this condition and can help identify underlying causes such as malnutrition, liver disease, kidney disease, or other conditions that affect protein production or loss.
Since symptoms of hypoproteinemia such as swelling, fatigue, and weakness can be associated with many other conditions, laboratory testing is essential for definitive diagnosis. A blood test that measures total protein levels provides the most direct assessment of this condition and helps healthcare providers determine the severity and guide appropriate treatment.
Normal total protein levels typically range from 6.0 to 8.3 grams per deciliter (g/dL). Results below this range may indicate hypoproteinemia. Your healthcare provider will interpret your results in the context of your symptoms and medical history to determine the underlying cause and appropriate treatment plan.
The information here is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for diagnosis and treatment.